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In Spatial Frequency Domain Imaging a sinusoidal intensity pattern is projected onto tissue, and the reflectance is a function of the projected spatial frequency and the tissue optical properties. For low spatial frequencies, the reflectance can be described by diffusion theory and Cuccia et al. developed a model based on the Partial Current Boundary Condition (PCBC) for the Diffusion Approximation. We show that an implicitly used approximation in the derivation by Cuccia et al. introduces errors in the estimated reflectance and tissue optical properties and we derive a new model that reduces these errors by a factor of 2.
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Anouk L. Post, Dirk J. Faber, Ton G. van Leeuwen, "Modeling the diffuse reflectance in spatial frequency domain imaging," Proc. SPIE PC12377, Optical Interactions with Tissue and Cells XXXIV, PC1237704 (7 March 2023); https://doi.org/10.1117/12.2650152