Assessment of the biomechanical impact of LASIK refractive surgery in human corneas using wave-based optical coherence elastography

Fernando Zvietcovich; Alejandra Varea; Judith Birkenfeld; Andrea Curatolo; Jesus Merayo-Lloves; Susana Marcos

doi:10.1117/12.3003433

13 March 2024 Assessment of the biomechanical impact of LASIK refractive surgery in human corneas using wave-based optical coherence elastography

Fernando Zvietcovich, Alejandra Varea, Judith Birkenfeld, Andrea Curatolo, Jesus Merayo-Lloves, Susana Marcos

Author Affiliations +

Proceedings Volume PC12844, Optical Elastography and Tissue Biomechanics XI; PC128440I (2024) https://doi.org/10.1117/12.3003433
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

The impact of LASIK surgery on corneal biomechanics remains unclear. To address this, we used air-coupled ultrasonic optical coherence elastography (ACUS-OCE) system to examine the full spatial-dependent elasticity of corneas before and after LASIK. We measured Lamb wave propagation speed and average corneal thickness in 16 semi-meridians to calculate the Shear Modulus (G) in 30 healthy control subjects (n=60 corneas) and 8 patients (n= 16 corneas) pre- and 1-month post-LASIK. G decreased from 52±4 kPa to 43±5 kPa after LASIK intervention. In summary, LASIK decreased corneal stiffness, which is consistent with the loss of anterior stroma containing high lamellae interweaving.

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Fernando Zvietcovich, Alejandra Varea, Judith Birkenfeld, Andrea Curatolo, Jesus Merayo-Lloves, and Susana Marcos "Assessment of the biomechanical impact of LASIK refractive surgery in human corneas using wave-based optical coherence elastography", Proc. SPIE PC12844, Optical Elastography and Tissue Biomechanics XI, PC128440I (13 March 2024); https://doi.org/10.1117/12.3003433

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