We present an initial study to describe the potential of optical coherence tomography (OCT) for characterizing
endomyocardial tissue. We obtained ventricular OCT images from 15 fresh human hearts. Layer thickness
measurements and texture features were extracted from volumetric datasets with endocardial thickening, normal
myocardium, myocardium with interstitial fibrosis, normal endocardium, and adipose tissue. Within our datasets, we
observed that the thickness of endocardium was not different within samples with normal or myocardium with interstitial
fibrosis, however samples with endocardial thickening showed statistically increased endocardial thickness.
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