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Photodynamic therapy (PDT) a new cancer treatment modality involves optical irradiation of photosensitized biological tissue. The activation of a photosensitizer is determined by the product of the absorption coefficient of the photosensitizer in the tissue and the light energy dose. Furthermore molecular oxygen is an essential part of the therapy. Hence the safety and efficacy of PDT depends on the accurate knowledge of the fluence light dose throughout the target tissue, knowledge of the photosensitizer concentration and partial oxygen pressure (p02).1-2
George Netchev
"Integrating cylinder for calibration of cylindrical diffusers and fluence and PO2 sensors", Proc. SPIE 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 103132E (29 August 2017); https://doi.org/10.1117/12.2283882
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George Netchev, "Integrating cylinder for calibration of cylindrical diffusers and fluence and PO2 sensors," Proc. SPIE 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 103132E (29 August 2017); https://doi.org/10.1117/12.2283882