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In digital holographic microscopy, one often obtains an in-focus image of the sample by applying a focus metric to a stack of numerical reconstructions. We present an alternative approach using a deep convolutional neural network.
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Tomi Pitkäaho, Aki Manninen, Thomas J. Naughton, "Focus classification in digital holographic microscopy using deep convolutional neural networks," Proc. SPIE 10414, Advances in Microscopic Imaging, 104140K (28 July 2017); https://doi.org/10.1117/12.2286161