Intraoperative photoacoustic screening: a breast surgical center experience

Ivan Kosik; Muriel Brackstone; Anat Kornecki; Astrid Chamson-Reig; Philip Wong; Morteza Heydari Araghi; Jeffrey J. L. Carson

doi:10.1117/12.2509552

27 February 2019 Intraoperative photoacoustic screening: a breast surgical center experience

Ivan Kosik, Muriel Brackstone, Anat Kornecki, Astrid Chamson-Reig, Philip Wong, Morteza Heydari Araghi, Jeffrey J. L. Carson

Author Affiliations +

Proceedings Volume 10878, Photons Plus Ultrasound: Imaging and Sensing 2019; 108780E (2019) https://doi.org/10.1117/12.2509552
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

High re-excision rates in breast conserving surgery call for a new intraoperative approach to the lumpectomy specimen evaluation problem. The unique intraoperative photoacoustic screening (iPAS) system, presented here, demonstrated the capability of photoacoustic tomography (PAT) to deliver optical sensitivity and specificity, along with over 2 cm imaging depth, in a true clinical setting. Highly specialized acoustic transducers enabled the evaluation of tumor extent, shape, morphology and position within lumpectomy specimens measuring up to 11 cm in diameter. Comparison with conventional ultrasound (US) and x-ray imaging validated the performance of iPAS. This approach shines a light towards more effective soft tissue abnormality assessment.

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Citation Download Citation

Ivan Kosik, Muriel Brackstone, Anat Kornecki, Astrid Chamson-Reig, Philip Wong, Morteza Heydari Araghi, and Jeffrey J. L. Carson "Intraoperative photoacoustic screening: a breast surgical center experience", Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108780E (27 February 2019); https://doi.org/10.1117/12.2509552

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