Virtual imaging trials: an emerging experimental paradigm in imaging research and practice

Ehsan Samei; Ehsan Abadi; Anuj Kapadia; Joseph Lo; Maciej Mazurowski; Paul Segars

doi:10.1117/12.2549818

16 March 2020 Virtual imaging trials: an emerging experimental paradigm in imaging research and practice

Ehsan Samei, Ehsan Abadi, Anuj Kapadia, Joseph Lo, Maciej Mazurowski, Paul Segars

Proceedings Volume 11312, Medical Imaging 2020: Physics of Medical Imaging; 113121T (2020) https://doi.org/10.1117/12.2549818
Event: SPIE Medical Imaging, 2020, Houston, Texas, United States

Abstract

As medical imaging technologies continue to accelerate in complexity, application, and multiplicity of design choices and use features, they should ideally be evaluated and optimized through human clinical trials. However, such trials are often impossible and impractical. Virtual imaging trials (VITs) offer a solution allowing scientists to conduct “human” trials of emerging imaging concepts and technologies via quick and cost effective simulations. VIT gives researchers a new experimental paradigm to answer fundamental questions that can only be practically answered using the precise controls and known ground truth afforded in the virtual domain. VIT is possible through realistic and accurate modeling of a) the patient, b) the imaging system, and c) the image interpretation process. This paper discusses these topics and offers demonstration examples of select applications of VIT in CT imaging.

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Citation Download Citation

Ehsan Samei, Ehsan Abadi, Anuj Kapadia, Joseph Lo, Maciej Mazurowski, and Paul Segars "Virtual imaging trials: an emerging experimental paradigm in imaging research and practice", Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 113121T (16 March 2020); https://doi.org/10.1117/12.2549818

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