Presentation
5 March 2021 Multimodal intrinsic contrast imaging for nerve discrimination in vivo
Graham A. Throckmorton, Justin S. Baba, Anita Mahadevan-Jansen
Author Affiliations +
Abstract
Inadvertent nerve injury is a common complication during many surgical procedures. Intraoperative localization of nerves could reduce the risk of nerve injury and improve patients’ quality of life post-operation. To address this need, we combine diffuse reflectance and polarization imaging techniques into a single imaging system for in vivo nerve mapping. Both modalities successfully localize nerves within the field of view in an in vivo rat model and together provide enhanced contrast in relation to the surrounding tissues. The results of this study provide valuable insight into the future development of a real-time imaging system for clinical translation.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Graham A. Throckmorton, Justin S. Baba, and Anita Mahadevan-Jansen "Multimodal intrinsic contrast imaging for nerve discrimination in vivo", Proc. SPIE 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX, 116310B (5 March 2021); https://doi.org/10.1117/12.2576531
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KEYWORDS
Nerve

In vivo imaging

Multimodal imaging

Diffuse reflectance spectroscopy

Imaging systems

Imaging spectroscopy

Polarization

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