Assessing a fiber probe-based approach to detect near infrared fluorescence for identifying and preserving parathyroid glands during neck surgeries

Giju Thomas; Emmanuel Mannoh; Melinda E. Sanders; Colleen M. Kiernan; Naira Baregamian; Carmen C. Solorzano; Anita Mahadevan-Jansen

doi:10.1117/12.2576823

5 March 2021 Assessing a fiber probe-based approach to detect near infrared fluorescence for identifying and preserving parathyroid glands during neck surgeries

Giju Thomas, Emmanuel Mannoh, Melinda E. Sanders, Colleen M. Kiernan, Naira Baregamian, Carmen C. Solorzano, Anita Mahadevan-Jansen

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Proceedings Volume 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX; 116310U (2021) https://doi.org/10.1117/12.2576823
Event: SPIE BiOS, 2021, Online Only

Abstract

Identifying parathyroid glands can be challenging for surgeons during head and neck operations. For the surgeon, it becomes essential to preserve healthy parathyroid glands, while successfully removing diseased parathyroid glands. This study presents PTeye – a commercial fiber probe-based device that was designed for intraoperative parathyroid identification by detecting near infrared autofluorescence. The results of this study demonstrate that PTeye had 95% accuracy in identifying parathyroid glands in 78 patients. The device had an overall detection rate of 97% for healthy and diseased parathyroid glands. PTeye could also quantify parathyroid vascularity in real-time by using indocyanine green during neck surgeries.

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Giju Thomas, Emmanuel Mannoh, Melinda E. Sanders, Colleen M. Kiernan, Naira Baregamian, Carmen C. Solorzano, and Anita Mahadevan-Jansen "Assessing a fiber probe-based approach to detect near infrared fluorescence for identifying and preserving parathyroid glands during neck surgeries", Proc. SPIE 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX, 116310U (5 March 2021); https://doi.org/10.1117/12.2576823

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KEYWORDS

Near infrared

Surgery

Fluorescence spectroscopy

Luminescence

Neck

Indocyanine green

Measurement devices

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