Portable visible and near-infrared spatial frequency domain imaging system to measure skin reactivity in response to noxious heating using a multi-spectral compound eye camera

Nandan Kumar Das; Saad Nagi; Keiichiro Kagawa; Jun Tanida; Rolf B. Saager

doi:10.1117/12.2577178

5 March 2021 Portable visible and near-infrared spatial frequency domain imaging system to measure skin reactivity in response to noxious heating using a multi-spectral compound eye camera

Nandan Kumar Das, Saad Nagi, Keiichiro Kagawa, Jun Tanida, Rolf B. Saager

Author Affiliations +

Proceedings Volume 11633, Design and Quality for Biomedical Technologies XIV; 116330G (2021) https://doi.org/10.1117/12.2577178
Event: SPIE BiOS, 2021, Online Only

Abstract

Detection of scattering and absorption properties in both visible and near-infrared regions are crucial to quantify multiple functional responses in tissue. We developed a compact, clinical spatial frequency domain imaging (SFDI) system around a custom, nine wavelength, compound-eye camera, spanning ~450-1000nm. In addition to the characterization and validation of this device, we performed a preliminary in-vivo investigation to evaluate the imager’s ability to characterize dermal response under a noxious heating protocol. Increases in hemoglobin and water concentration are detected as well as slight alterations in the reduced scattering spectrum that maybe correlated with cellular and extra-cellular reactivity.

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Nandan Kumar Das, Saad Nagi, Keiichiro Kagawa, Jun Tanida, and Rolf B. Saager "Portable visible and near-infrared spatial frequency domain imaging system to measure skin reactivity in response to noxious heating using a multi-spectral compound eye camera", Proc. SPIE 11633, Design and Quality for Biomedical Technologies XIV, 116330G (5 March 2021); https://doi.org/10.1117/12.2577178

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