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5 March 2021 Combined optical coherence tomography and broadband single fiber reflectance spectroscopy
Xavier Attendu, Paul R. Bloemen, Niels H. Kind, Daniel M. de Bruin, Dirk J. Faber, Caroline Boudoux, Ton G. van Leeuwen
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Proceedings Volume 11634, Multimodal Biomedical Imaging XVI; 1163403 (2021) https://doi.org/10.1117/12.2578129
Event: SPIE BiOS, 2021, Online Only
Abstract
We present a bi-modal bench-top system combining OCT with broadband, single-fiber reflectance spectroscopy. This combination aims to address the limited molecular sensitivity of standard OCT imaging in order to obtain co-registered morphological and molecular information. We present various technical innovations for this work, including an all-reflective scanner head with adaptive optic components for focus scanning and reduction of field curvature. Furthermore, we demonstrate the use of specialty fiber components to obtain multiple illumination schemes for the spectroscopic channel and enhance the spatially resolved reconstruction of optical properties.
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Xavier Attendu, Paul R. Bloemen, Niels H. Kind, Daniel M. de Bruin, Dirk J. Faber, Caroline Boudoux, and Ton G. van Leeuwen "Combined optical coherence tomography and broadband single fiber reflectance spectroscopy", Proc. SPIE 11634, Multimodal Biomedical Imaging XVI, 1163403 (5 March 2021); https://doi.org/10.1117/12.2578129
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KEYWORDS
Optical coherence tomography
Reflectance spectroscopy
Head
Scanners
Chromatic aberrations
Imaging systems
Multimode fibers
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