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5 March 2021 Ultrasound-mediated hyperthermia with the guidance of x-ray-induced radiation acoustic imaging
Kai-Wei Chang, Wei Zhang, Paul L. Carson, Issam El Naqa, Xueding Wang
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Proceedings Volume 11642, Photons Plus Ultrasound: Imaging and Sensing 2021; 1164211 (2021) https://doi.org/10.1117/12.2576427
Event: SPIE BiOS, 2021, Online Only
Abstract
A new concept to achieve ultrasound-mediated hyperthermia (USHT) with the guidance of X-ray-induced radiation acoustic imaging (xRAI) is proposed. During radiation therapy of cancer patients, the received acoustic signals for xRAI can be used to correct the aberration caused by inhomogeneous acoustic property of human skull and provide guidance for focused ultrasound to achieve USHT with the same ultrasound array at the X-ray dose deposition area. To prove this concept, simulations with a human head model were made for both point targets and a tumor volume. The focused acoustic patterns with and without xRAI-based aberration correction were compared. The feasibility of this xRAI-guided USHT concept was further demonstrated by experimental studies using a human skull.
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Kai-Wei Chang, Wei Zhang, Paul L. Carson, Issam El Naqa, and Xueding Wang "Ultrasound-mediated hyperthermia with the guidance of x-ray-induced radiation acoustic imaging", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 1164211 (5 March 2021); https://doi.org/10.1117/12.2576427
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KEYWORDS
Ultrasonography
Acoustics
Head
Transducers
Magnetic resonance imaging
Real time imaging
Tumors
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