Multiparameter optical methods and instruments for the diagnostics of human body microcirculatory-tissue systems

Andrey Dunaev

doi:10.1117/12.2590817

4 May 2021 Multiparameter optical methods and instruments for the diagnostics of human body microcirculatory-tissue systems

Andrey Dunaev

Author Affiliations +

Proceedings Volume 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine; 1184505 (2021) https://doi.org/10.1117/12.2590817
Event: Saratov Fall Meeting 2020, 2020, Saratov, Russian Federation

Abstract

Multiparameter optical non-invasive diagnostics (mOND) combining several methods in a single device is one of the most promising technologies for studying human microcirculatory-tissue systems (MTS). This allows one to obtain highly efficient diagnostic tools for rheumatology, endocrinology, surgery, oncology, neurology, and other areas of medicine, as it is necessary to determine the parameters of the perfusion-metabolic status of tissues. However, there are a number of limitations related to its insufficient methodological and instrumental support. This work is devoted to systematizing of the relationship between the main parameters and states of MTS in various diseases and OND methods, as well as developing a formalized scheme for the synthesis of mOND methods. The aim was to substantiate and develop a methodology for mOND to assess the functional state of the MTS of the human body, and to demonstrate an example of mOND implementation in minimally invasive surgery. The results can be extended to other areas of medicine, for example, to improve these methods in rheumatology, endocrinology, otolaryngology, dermatology, neurology, etc.

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Andrey Dunaev "Multiparameter optical methods and instruments for the diagnostics of human body microcirculatory-tissue systems", Proc. SPIE 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine, 1184505 (4 May 2021); https://doi.org/10.1117/12.2590817

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