Deep confocal fluorescence microscopy with single-photon superconducting nanowire detector

Fei Xia; Monique Gevers; Andreas Fognini; Aaron T. Mok; Bo Li; Najva Akabri; Iman Esmaeil Zadeh; Jessie Qin-Dregely; Chris Xu

doi:10.1117/12.2620775

30 May 2022 Deep confocal fluorescence microscopy with single-photon superconducting nanowire detector

Fei Xia, Monique Gevers, Andreas Fognini, Aaron T. Mok, Bo Li, Najva Akabri, Iman Esmaeil Zadeh, Jessie Qin-Dregely, Chris Xu

Author Affiliations +

Proceedings Volume 12089, Advanced Photon Counting Techniques XVI; 1208905 (2022) https://doi.org/10.1117/12.2620775
Event: SPIE Defense + Commercial Sensing, 2022, Orlando, Florida, United States

Abstract

Using short-wave infrared wavelength advantages, we demonstrate one-photon fluorescence confocal microscopy of adult mouse brains with penetration depths up to 1.7mm. This is achieved by labeling quantum dots with 1300 nm excitation and 1700 nm emission and detecting them with a single-photon superconducting nanowire detector.

Conference Presentation

Citation Download Citation

Fei Xia, Monique Gevers, Andreas Fognini, Aaron T. Mok, Bo Li, Najva Akabri, Iman Esmaeil Zadeh, Jessie Qin-Dregely, and Chris Xu "Deep confocal fluorescence microscopy with single-photon superconducting nanowire detector", Proc. SPIE 12089, Advanced Photon Counting Techniques XVI, 1208905 (30 May 2022); https://doi.org/10.1117/12.2620775

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