Real-time line-field OCT using low-cost high-speed camera

Kai Neuhaus; Shuibin Ni; Shanjida Khan; Omkar Tharawe; Siyu Chen; David Huang; Yifan Jian

doi:10.1117/12.2652656

8 March 2023 Real-time line-field OCT using low-cost high-speed camera

Kai Neuhaus, Shuibin Ni, Shanjida Khan, Omkar Tharawe, Siyu Chen, David Huang, Yifan Jian

Proceedings Volume 12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; 123670F (2023) https://doi.org/10.1117/12.2652656
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

A real-time high-speed line-field optical coherence tomography (LFOCT) configuration at 5,000 B-frames or 2,500,000 A-lines per second for clinical applications is described. The development of the LFOCT technology has experienced increasing interest despite the challenge of achieving sufficient sensitivity and resolution due to crosstalk. Publications of research systems usually apply expensive infrared cameras to improve image quality. The costs, complexity, and lack of real-time data transfer of dedicated highspeed IR cameras make it challenging to employ LFOCT for a more comprehensive application range. We demonstrate using a comparatively low-cost, high-speed camera for real-time data transfer and image display in conjunction with a light source at a center wavelength of 840 nm and a bandwidth of 50 nm. Although the camera and available sample power limits the sensitivity (75 dB), we can demonstrate imaging on a human fingertip (in vivo) and the cornea of a rabbit eye. Further development of the system will focus on compensating for the camera's limited sensitivity and improving resolution to target clinical in vivo imaging such as ophthalmic applications.

Conference Presentation

Citation Download Citation

Kai Neuhaus, Shuibin Ni, Shanjida Khan, Omkar Tharawe, Siyu Chen, David Huang, and Yifan Jian "Real-time line-field OCT using low-cost high-speed camera", Proc. SPIE 12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, 123670F (8 March 2023); https://doi.org/10.1117/12.2652656

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