High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy

Robin Dale; Thomas D. O'Sullivan; Scott Howard; Chris Campbell; Felipe Orihuela-espina; Hamid Dehghani

doi:10.1117/12.2651676

7 March 2023 High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy

Robin Dale, Thomas D. O'Sullivan, Scott Howard, Chris Campbell, Felipe Orihuela-espina, Hamid Dehghani

Proceedings Volume 12376, Optical Tomography and Spectroscopy of Tissue XV; 1237606 (2023) https://doi.org/10.1117/12.2651676
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Frequency domain (FD) diffuse optical spectroscopy (DOS) can be used to recover absolute optical properties of biological tissue, providing valuable clinical feedback, including in diagnosis and monitoring of breast tumours. In this study, tomographic (3D) and topographic (2D) techniques for spatially-varying optical parameter recovery are presented, based on a multi-distance, handheld DOS probe. Processing pipelines and reconstruction quality are discussed and quantitatively compared, demonstrating the trade-offs between depth sensitivity, optical contrast, and computational speed. Together, the two techniques provide both depth sensitive real-time feedback, and high-resolution 3D reconstruction from a single set of measurements, enabling faster and more accurate clinical feedback.

Conference Presentation

Citation Download Citation

Robin Dale, Thomas D. O'Sullivan, Scott Howard, Chris Campbell, Felipe Orihuela-espina, and Hamid Dehghani "High-speed spatial parameter recovery using multi-distance frequency-domain diffuse optical spectroscopy", Proc. SPIE 12376, Optical Tomography and Spectroscopy of Tissue XV, 1237606 (7 March 2023); https://doi.org/10.1117/12.2651676

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