Simulated retinal layers to study optical coherence tomography imaging

Abira Bright B; Lakshmi Parvathi M.; Vani Damodaran

doi:10.1117/12.2672169

11 May 2023 Simulated retinal layers to study optical coherence tomography imaging

Abira Bright B, Lakshmi Parvathi M., Vani Damodaran

Proceedings Volume 12638, Women in Optics and Photonics in India 2022; 1263814 (2023) https://doi.org/10.1117/12.2672169
Event: Women in Optics and Photonics in India, 2022, Bangalore, India

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Abstract

Optical Coherence Tomography (OCT) is a non-invasive optical imaging technique capable of producing high-resolution cross-sectional 2D and 3D images of non-homogeneous samples, such as biological tissue. It is a gold standard in retinal imaging. In this work, an analytical model of the retina is developed to investigate the scientific principles of the OCT system. The Michelson interferometer configuration is modeled in Matlab using standard interferometric equations. A broadband light source centered at 840 nm with a spectral width of 46 nm with a Gaussian profile is modeled. The retina is simulated with a few layers of refractive indices based on the values reported so far in the literature. The final interferogram based on the above model and sample is obtained and analyzed in both time domain (TD) and spectral domain (SD) OCT configuration and an A-scan is generated. The A-scan obtained clearly shows the boundary between the layers with intensity dependent on the change in refractive index between layers and the amount of light available at each layer.

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Abira Bright B, Lakshmi Parvathi M., and Vani Damodaran "Simulated retinal layers to study optical coherence tomography imaging", Proc. SPIE 12638, Women in Optics and Photonics in India 2022, 1263814 (11 May 2023); https://doi.org/10.1117/12.2672169

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