Optimization design of the coupling scheme of the pulse laser output through the hysteroscope observation channel

Jinrui Wang; Chuanhui Ge; Guansong Zou; Feiyang Wang; Xiaoman Zhang; Shulian Wu; Hengchang Guo; Huan Yi; Yulong Zhang; Hui Li

doi:10.1117/12.2682773

18 July 2023 Optimization design of the coupling scheme of the pulse laser output through the hysteroscope observation channel

Jinrui Wang, Chuanhui Ge, Guansong Zou, Feiyang Wang, Xiaoman Zhang, Shulian Wu, Hengchang Guo, Huan Yi, Yulong Zhang, Hui Li

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Proceedings Volume 12745, Sixteenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2023); 127450O (2023) https://doi.org/10.1117/12.2682773
Event: Sixteenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2023), 2023, Haikou, China

Abstract

Photoacoustic imaging is an imaging technology which combines the advantages of high-resolution optical imaging and deep detection depth of acoustic imaging. Photoacoustic imaging combined with hysteroscopy may be a new diagnostic technique for endometrial cancer. However, the energy loss after pulsed laser passing through the hysteroscope is very large. Therefore, the energy of pulsed laser after hysteroscopy based on photoacoustic imaging is worth further discussion. A coupling Program of pulsed laser and hysteroscope based on the optical path of pulsed laser and hysteroscope was designed in this paper. The Program was optimized by ZEMAX simulation, and then the optimal effect of pulsed laser observation through hysteroscopy was verified by phantom experiment. The results show that the pulsed laser can obtain better photoacoustic signals after passing through our coupling module. This method is expected to be applied to the detection of endometrial diseases in clinic.

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Jinrui Wang, Chuanhui Ge, Guansong Zou, Feiyang Wang, Xiaoman Zhang, Shulian Wu, Hengchang Guo, Huan Yi, Yulong Zhang, and Hui Li "Optimization design of the coupling scheme of the pulse laser output through the hysteroscope observation channel", Proc. SPIE 12745, Sixteenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2023), 127450O (18 July 2023); https://doi.org/10.1117/12.2682773

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KEYWORDS

Pulsed laser operation

Photoacoustic spectroscopy

Signal detection

Cancer detection

Design and modelling

Cancer

Photoacoustic imaging

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