A comparative study of detecting relative glycation of porcine oral mucosa and skin

Nasim Kamely; Sohidul Mondal; Madhusudan Roy; Mei-Chun Lin; Chih-Yu Leu; Anupama Nair; Pei-Jen Lou; Shean-Jen Chen; Chen-Yuan Dong

doi:10.1117/12.2691282

12 March 2024 A comparative study of detecting relative glycation of porcine oral mucosa and skin

Nasim Kamely, Sohidul Mondal, Madhusudan Roy, Mei-Chun Lin, Chih-Yu Leu, Anupama Nair, Pei-Jen Lou, Shean-Jen Chen, Chen-Yuan Dong

Author Affiliations +

Proceedings Volume 12847, Multiphoton Microscopy in the Biomedical Sciences XXIV; 128470L (2024) https://doi.org/10.1117/12.2691282
Event: SPIE BiOS, 2024, San Francisco, California, United States

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Abstract

In this study, we performed two-photon imaging of porcine skin and oral mucosa specimens under simulated tissue glycation. After 14 days of glycation treatment with fructose, AGEs were formed in both porcine skin and oral mucosa. The autofluorescence response of both skin and mucosa depended on the detection bandwidth with the wavelength region of 330-480 nm demonstrated the strongest detection of AGE autofluorescence.

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Nasim Kamely, Sohidul Mondal, Madhusudan Roy, Mei-Chun Lin, Chih-Yu Leu, Anupama Nair, Pei-Jen Lou, Shean-Jen Chen, and Chen-Yuan Dong "A comparative study of detecting relative glycation of porcine oral mucosa and skin", Proc. SPIE 12847, Multiphoton Microscopy in the Biomedical Sciences XXIV, 128470L (12 March 2024); https://doi.org/10.1117/12.2691282

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