Comparison of optical and photoacoustic response of laser-synthesized TiN nanoparticles

I. V. Lunyov; M. S. Savinov; A. V. Kabashin; A. A. Popov

doi:10.1117/12.3009022

12 March 2024 Comparison of optical and photoacoustic response of laser-synthesized TiN nanoparticles

I. V. Lunyov, M. S. Savinov, A. V. Kabashin, A. A. Popov

Proceedings Volume 12874, Nanoscale and Quantum Materials: From Synthesis and Laser Processing to Applications 2024; 128740B (2024) https://doi.org/10.1117/12.3009022
Event: SPIE LASE, 2024, San Francisco, California, United States

Abstract

Photoacoustic Imaging (PAI) has emerged as a powerful imaging technique that combines advantages of optical absorption contrast with the ability to penetrate deep into biological tissues using ultrasound waves. Exogenous chromophores, including light-absorbing nanoparticles (NPs), can significantly enhance the photoacoustic response and provide photoacoustic contrast for various regions in organism. We recently introduced laser-synthesized TiN NPs as a promising alternative plasmonic nanomaterial, having exceptionally high optical absorption in the window of biological tissue transparency. In this study, we continue our evaluation of laser-synthesized TiN NPs as a contrast agent for PAI by comparative studying of optical and photoacoustic response of tissue-mimicking phantoms containing TiN NPs. We demonstrated that laser-synthesized TiN NPs preserve their superior photoacoustic performance in the conditions of tissue-like media. Our results confirm high potential of TiN NPs to serve as an effective exogenous contrast agent for PAI.

Conference Presentation

Citation Download Citation

I. V. Lunyov, M. S. Savinov, A. V. Kabashin, and A. A. Popov "Comparison of optical and photoacoustic response of laser-synthesized TiN nanoparticles", Proc. SPIE 12874, Nanoscale and Quantum Materials: From Synthesis and Laser Processing to Applications 2024, 128740B (12 March 2024); https://doi.org/10.1117/12.3009022

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