Multivariate determination of blood substrates in human plasma by FT-NIR spectroscopy

Herbert Michael Heise; Ralf Marbach; Th. Koschinsky; F. A. Gries

doi:10.1117/12.56396

1 March 1992 Multivariate determination of blood substrates in human plasma by FT-NIR spectroscopy

Herbert Michael Heise, Ralf Marbach, Th. Koschinsky, F. A. Gries

Proceedings Volume 1575, 8th Intl Conf on Fourier Transform Spectroscopy; (1992) https://doi.org/10.1117/12.56396
Event: Eighth International Conference on Fourier Transform Spectroscopy, 1991, Lubeck-Travemunde, Germany

Abstract

A spectral analysis of human EDTA plasma from 124 different patients was undertaken using an FT-NIR spectrometer. Optimized intervals of the absorbance spectra were considered for the PLS-calibrations with reference concentrations from standard clinical methods determined in triplicate. The following relative prediction errors were achieved: total protein 1.4%, cholesterol 3.8%, triglycerides 8.6%, glucose 9.1%, and urea 18.6%.

Citation Download Citation

Herbert Michael Heise, Ralf Marbach, Th. Koschinsky, and F. A. Gries "Multivariate determination of blood substrates in human plasma by FT-NIR spectroscopy", Proc. SPIE 1575, 8th Intl Conf on Fourier Transform Spectroscopy, (1 March 1992); https://doi.org/10.1117/12.56396

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