Multichannel fiber system for luminescence diagnostics of tumors

Victor B. Loschenov; M. V. Baryshev; Natalia N. Zharkova; Vjacheslav G. Artioushenko; Alexander Krjukov; Alexander Startsev; Kelly B. Moran; Joseph D. Brown

doi:10.1117/12.60232

1 August 1992 Multichannel fiber system for luminescence diagnostics of tumors

Victor B. Loschenov, M. V. Baryshev, Natalia N. Zharkova, Vjacheslav G. Artioushenko, Alexander Krjukov, Alexander Startsev, Kelly B. Moran, Joseph D. Brown

Author Affiliations +

Proceedings Volume 1649, Optical Fibers in Medicine VII; (1992) https://doi.org/10.1117/12.60232
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Fiber-optic catheters currently in use make it impossible to solve the main problem of spectral fluorescence diagnostics and to provide the high accuracy and reproducibility of in vivo tissue fluorescence investigations. It is well known that fluorescence signal intensity is varied with distance and angle between the biological tissue and the distal tip of the catheter. Signal intensity also depends on the arrangement of light delivery fibers relative to light collecting fibers. Taking these things into account, we developed a design for catheters which allows them to perform the endoscopical diagnostics of tumors with substantial reduction of confusing influences. The new catheters have been tested in preclinical and clinical practice. Their design fits the requirements of certain diagnostic aims, but could also be specified for other applications: measurements of reflection and scattering characteristics of the object, plasma emission spectra (during lithotripsy or angioplasty), etc. There also are wide areas of possible applications for spectra measurements of gaseous, liquid, or solid substances in biology and chemistry.

Citation Download Citation

Victor B. Loschenov, M. V. Baryshev, Natalia N. Zharkova, Vjacheslav G. Artioushenko, Alexander Krjukov, Alexander Startsev, Kelly B. Moran, and Joseph D. Brown "Multichannel fiber system for luminescence diagnostics of tumors", Proc. SPIE 1649, Optical Fibers in Medicine VII, (1 August 1992); https://doi.org/10.1117/12.60232

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available