Effects of pulsed mid-IR lasers on bovine knee joint tissues

Sandor G. Vari M.D.; Wei-Qiang Shi; Vani R. Pergadia; J. Timothy Duffy; J. M. Miller; Maurits J. van der Veen; Andrew B. Weiss; Michael C. Fishbein M.D.; Warren S. Grundfest M.D.

doi:10.1117/12.148330

21 July 1993 Effects of pulsed mid-IR lasers on bovine knee joint tissues

Sandor G. Vari M.D., Wei-Qiang Shi, Vani R. Pergadia, J. Timothy Duffy, J. M. Miller, Maurits J. van der Veen, Andrew B. Weiss, Michael C. Fishbein M.D., Warren S. Grundfest M.D.

Author Affiliations +

Proceedings Volume 1880, Lasers in Orthopedic, Dental, and Veterinary Medicine II; (1993) https://doi.org/10.1117/12.148330
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

We investigated the effect of varying Tm:YAG (2.014 micrometers ) and Ho:YAG (2.130 micrometers ) laser parameters on ablation rate and consequent thermal damage. Mid-infrared wavelengths are strongly absorbed by most biological tissues due to the tissue's high water content. The ablation rate of fresh bovine knee joint tissues (fibrous cartilage, hyaline cartilage, and bone) in saline was assessed as a function of radiant exposure (160 - 950 J/cm²), at pulse widths of 200 microsecond(s) ec for Tm:YAG and 250 microsecond(s) ec for Ho:YAG and a repetition rate of 2 Hz. All tissues used in this study could be efficiently ablated using two micron lasers. The mechanism of action is likely related to the formation and collapse of cavitation bubbles, associated with mid-infrared lasers. We concluded that the Tm:YAG and Ho:YAG lasers are capable of effective knee joint tissue ablation.

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Sandor G. Vari M.D., Wei-Qiang Shi, Vani R. Pergadia, J. Timothy Duffy, J. M. Miller, Maurits J. van der Veen, Andrew B. Weiss, Michael C. Fishbein M.D., and Warren S. Grundfest M.D. "Effects of pulsed mid-IR lasers on bovine knee joint tissues", Proc. SPIE 1880, Lasers in Orthopedic, Dental, and Veterinary Medicine II, (21 July 1993); https://doi.org/10.1117/12.148330

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