Preliminary investigation into the analytical potential of the fiber-drop analyzer for body-fluid analysis

Norman Douglas McMillan; Eon O'Mongain; James Edward Walsh; Dermot Orr; Z. C. Ge; V. Lawlor

doi:10.1117/12.163705

2 December 1993 Preliminary investigation into the analytical potential of the fiber-drop analyzer for body-fluid analysis

Norman Douglas McMillan, Eon O'Mongain, James Edward Walsh, Dermot Orr, Z. C. Ge, V. Lawlor

Author Affiliations +

Proceedings Volume 2005, Optical Diagnostics in Fluid and Thermal Flow; (1993) https://doi.org/10.1117/12.163705
Event: SPIE's 1993 International Symposium on Optics, Imaging, and Instrumentation, 1993, San Diego, CA, United States

Abstract

A preliminary study has been made into the temporal and spectral characteristics of internally illuminated liquid drops using the Fiber Drop Analyzer (FDA) with the objective of using this instrument for the diagnosis of disease in synovial fluid based on measurements of viscosity, absorbance and other parameters. Two approaches to the measurement of viscosity are identified and described. This study describes for the first time the operation of a multiwavelength FDA. Spectral absorbance of liquids containing 10 ppb rhodamine-b are made and the sensitivity of the FDA compared with standard spectra-photometric techniques. The variation in returned signal as a function of drop growth phase obtained from three water based solutions are qualitatively investigated and the understanding of the measurement potential of the instrument system is discussed.

Citation Download Citation

Norman Douglas McMillan, Eon O'Mongain, James Edward Walsh, Dermot Orr, Z. C. Ge, and V. Lawlor "Preliminary investigation into the analytical potential of the fiber-drop analyzer for body-fluid analysis", Proc. SPIE 2005, Optical Diagnostics in Fluid and Thermal Flow, (2 December 1993); https://doi.org/10.1117/12.163705

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