Intraoperative photodynamic therapy on spontaneous canine nasal tumors

Diego Fonda; Carlo Maria Mortellaro; Stefano Romussi; Paola Taroni; Rinaldo Cubeddu

doi:10.1117/12.184947

7 September 1994 Intraoperative photodynamic therapy on spontaneous canine nasal tumors

Diego Fonda, Carlo Maria Mortellaro, Stefano Romussi, Paola Taroni, Rinaldo Cubeddu

Proceedings Volume 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV; (1994) https://doi.org/10.1117/12.184947
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Promising results obtained by photodynamic therapy (PDT) with porphyrins on superficial spontaneous canine tumors suggested the experiment of this technique on intracavitary tumors, specifically at the endonasal site. The supposed neoplastic residual bed was irradiated directly during surgery at the end of the debulking. Five dogs referred to the surgical department of the veterinary school, University of Milan and affected by endonasal neoplasias were submitted to PDT after radiologic and cyto-histologic diagnosis and TNM stadiation. All the selected tumors were included in the clinical stage 1 (T1NOMO). Mean and median survival time (from the day of treatment) were 11.6 - 5.4 and 12 months, respectively. Different staging of the treated tumors limits the possibility of an objective comparison with other alternative therapeutic procedures.

Citation Download Citation

Diego Fonda, Carlo Maria Mortellaro, Stefano Romussi, Paola Taroni, and Rinaldo Cubeddu "Intraoperative photodynamic therapy on spontaneous canine nasal tumors", Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); https://doi.org/10.1117/12.184947

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