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A tubular optical probe for fluorescent immunosensors based on magnetic focusing of paramagnetic microspheres has been developed. The optical probe features a tubular optical waveguide tapered at both ends with a tapered magnet embedded inside the waveguide. Laser light is delivered to a dye-labeled spot in the inner surface of a cuvette and the fluorescent signal is guided to an optical detection system. A 3D computer model of this system has been created and its optical properties evaluated with a commercially available non-sequential ray-trace program. Up to 10,000 rays are traced from the laser to the cuvette and again from the fluorescent source to the detector. Results lead to the optimization of the component properties.
He Cao,Arthur Garth Rand, andStephen V. Letcher
"Modeling of a tapered tubular optical waveguide probe for fluorescent immunosensors", Proc. SPIE 4077, International Conference on Sensors and Control Techniques (ICSC 2000), (9 May 2000); https://doi.org/10.1117/12.385542
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He Cao, Arthur Garth Rand, Stephen V. Letcher, "Modeling of a tapered tubular optical waveguide probe for fluorescent immunosensors," Proc. SPIE 4077, International Conference on Sensors and Control Techniques (ICSC 2000), (9 May 2000); https://doi.org/10.1117/12.385542