5-aminolevulinic-acid (ALA) induced fluorescence for laparoscopic diagnosis of peritoneal metastasis: an experimental study

Michel Canis; R. Botchorishvili; N. Berreni; H. Manhes; A. Wattiez; G. Mage; J. L. Pouly; M. A. Bruhat

doi:10.1117/12.413717

31 January 2001 5-aminolevulinic-acid (ALA) induced fluorescence for laparoscopic diagnosis of peritoneal metastasis: an experimental study

Michel Canis, R. Botchorishvili, N. Berreni, H. Manhes, A. Wattiez, G. Mage, J. L. Pouly, M. A. Bruhat

Author Affiliations +

Proceedings Volume 4156, Clinical Lasers and Diagnostics; (2001) https://doi.org/10.1117/12.413717
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Ovarian cancer is the most frequent cause of gynecologic cancer-related death in the United States. In patients with advanced disease, the initial steps of the treatment, surgical debulking and chemotherapy are efficacious as evidenced by negative second look laparotomies or laparoscopies. However 1 5% to 50% of the patients with negative second look will subsequently experience recurring disease whithin 5 years and will inevitably die from the disease.(1) Therefore any approach which would improve the sensitivity and decrease the invasiveness of this procedure would be very attractive to improve the management and the quality of life of these patients.

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Michel Canis, R. Botchorishvili, N. Berreni, H. Manhes, A. Wattiez, G. Mage, J. L. Pouly, and M. A. Bruhat "5-aminolevulinic-acid (ALA) induced fluorescence for laparoscopic diagnosis of peritoneal metastasis: an experimental study", Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); https://doi.org/10.1117/12.413717

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