Normalized-constraint method for minimizing interparameter cross-talk in reconstructed images of spatially heterogeneous scattering and absorption coefficients

Yaling Pei; Harry L. Graber; Randall Locke Barbour

doi:10.1117/12.434481

29 June 2001 Normalized-constraint method for minimizing interparameter cross-talk in reconstructed images of spatially heterogeneous scattering and absorption coefficients

Yaling Pei, Harry L. Graber, Randall Locke Barbour

Author Affiliations +

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434481
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

In this report, we present a method to reduce the cross-talk problem in optical tomography. The method described is an extension of a previously reported perturbation formulation related to relative detector values, and employs a weight matrix scaling technique together with a constrained CGD method for imaging reconstruction. Results from numerical and experimental studies using DC measurement data demonstrate that the approach can effectively isolate absorption and scattering heterogeneities, even for complex combinations of perturbations in optical properties. The derive method is remarkably stable to errors originating from an insufficiently accurate estimate of properties of the reference medium.

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Yaling Pei, Harry L. Graber, and Randall Locke Barbour "Normalized-constraint method for minimizing interparameter cross-talk in reconstructed images of spatially heterogeneous scattering and absorption coefficients", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434481

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