Photoacoustic imaging of blood perfusion in tissue and phantoms

Magdalena C. Pilatou; Roy G. M. Kolkman; Erwin Hondebrink; Rene Alexander Bolt; Frits F. M. de Mul

doi:10.1117/12.429318

15 June 2001 Photoacoustic imaging of blood perfusion in tissue and phantoms

Magdalena C. Pilatou, Roy G. M. Kolkman, Erwin Hondebrink, Rene Alexander Bolt, Frits F. M. de Mul

Author Affiliations +

Proceedings Volume 4256, Biomedical Optoacoustics II; (2001) https://doi.org/10.1117/12.429318
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

To localize and monitor the blood content in tissue we developed a very sensitive photo-acoustical detector. PVDF has been used as piezo-electric material. In this detector also fibers for the illumination of the sample are integrated. Resolution is about 20 (m in depth and about 50-100 m laterally). We use 532 nm light. We will show how photoacoustics can be used for measuring the thickness of tissue above bone. We will also report measurements on tissue phantoms: e.g. a vessel delta from the epigastric artery branching of a Wistar rat, filled with an artificial blood-resembling absorber. The measurements have been carried out on phantoms containing vessels at several depths. Signal processing was enhanced by Fourier processing of the data.

Citation Download Citation

Magdalena C. Pilatou, Roy G. M. Kolkman, Erwin Hondebrink, Rene Alexander Bolt, and Frits F. M. de Mul "Photoacoustic imaging of blood perfusion in tissue and phantoms", Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); https://doi.org/10.1117/12.429318

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