Nonablative remodeling: a 14-month clinical ultrasound-imaging profilometric evaluation of a 1540-nm Er:Glass laser

Nathalie Fournier; Serge Dahan; Gilbert Barneon; Celine Rouvrais; Stephane Diridollou; Jean-Michel Lagarde; Serge R. Mordon

doi:10.1117/12.486605

15 October 2002 Nonablative remodeling: a 14-month clinical ultrasound-imaging profilometric evaluation of a 1540-nm Er:Glass laser

Nathalie Fournier, Serge Dahan, Gilbert Barneon, Celine Rouvrais, Stephane Diridollou, Jean-Michel Lagarde, Serge R. Mordon

Author Affiliations +

Proceedings Volume 4903, Laser Florence 2001: A Window on the Laser Medicine World; (2002) https://doi.org/10.1117/12.486605
Event: Laser Florence 2001: a Window on the Laser Medicine World, 2001, Florence, Italy

Abstract

Background: Non-ablative remodeling has been recently proposed as a new anti-ageing treatment with no downtime. Objective: To evaluate the efficacy and safety of non-ablative skin remodeling with a 1540 nm Er:Glass laser and contact cooling on pen-oral and pen-orbital rhytids at 14 months follow up. Methods: 42 female patients (mean age: 47 years), Fitzpatrick skin types I -IV were treated five times at 6 weeks intervals, and checked 6 months after the last treatment . Patients were evaluated using clinical data, patients satisfaction (scale 1 to 4), digital pictures, ultrasound imaging and profilometry data from silicone imprints in order to quantify the degree of improvement. Results: All subjects reported an improvement in the quality and visual aspect of their skin at 6 months (mean patient's satisfaction : 3,06/4) and they noticed that it was very similar at 14 months after enrollment (mean patient's satisfaction: 2.9/4) . This was confirmed by a 43.2% reduction ofanisotropy (p<O.OO1) six weeks after the 4th treatment, and even 49.5 % reduction 6 weeks after the 5th treatment. Ultrasound imaging demonstrated a 17% increase of the dermis thickness (p<O.OO5) 1 month after the 3rd freatment and still 1 1% increase 6 months after the last treatment. A lack of immediate or late adverse effects was noted at all stages ofthe procedure. Conclusion: This study demonstrated that irradiation with a 1540nm Er:Glass laser emitting in a pulsed mode and coupled with an efficient cooling system , increases dermis thickness, reduces the anisotropy ofthe skin and finally improves clinical aspects. The lack of adverse effects confirmed that all this procedure was safe.

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Nathalie Fournier, Serge Dahan, Gilbert Barneon, Celine Rouvrais, Stephane Diridollou, Jean-Michel Lagarde, and Serge R. Mordon "Nonablative remodeling: a 14-month clinical ultrasound-imaging profilometric evaluation of a 1540-nm Er:Glass laser", Proc. SPIE 4903, Laser Florence 2001: A Window on the Laser Medicine World, (15 October 2002); https://doi.org/10.1117/12.486605

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