Application of LED imager for breast cancer diagnosis

Jun Zhang; Yuanqing Lin; Shoko Nioka; Nancy O'Connor; Brian Czerniecki; Emily F. Conant; Britton Chance

doi:10.1117/12.482933

12 September 2002 Application of LED imager for breast cancer diagnosis

Jun Zhang, Yuanqing Lin, Shoko Nioka, Nancy O'Connor, Brian Czerniecki, Emily F. Conant, Britton Chance

Proceedings Volume 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment; (2002) https://doi.org/10.1117/12.482933
Event: Photonics Asia, 2002, Shanghai, China

Abstract

This paper focuses on breast cancer diagnosis using the newly developed low-noise threewavelength (?=730nm, 805nm and 850nm) NIR light emitting diode (LED) continuous-wave (CW) imager. The NIR CW imager has its advantage of simplicity, and potential for a portable instrument. The imaging rate is 5 frame/second. The signal to noise ratio is larger than 2000 when measuring at a breast model ( ?a=0.04/cm, ?'= 8/cm), which corresponds to 4x 10-4 optical density (OD) error. Phantom test was carried out, and indicated good localization of heterogeneity. It was known that cancer has more blood concentration and de-oxygenation than normal tissue, which is the principle of breast cancer detection using NIR spectroscopy. Clinical results of breast cancer studies will be presented. Keywords: LED, Breast Cancer Imaging, CW

Citation Download Citation

Jun Zhang, Yuanqing Lin, Shoko Nioka, Nancy O'Connor, Brian Czerniecki, Emily F. Conant, and Britton Chance "Application of LED imager for breast cancer diagnosis", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); https://doi.org/10.1117/12.482933

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