Physiological meaning of cerebral oxygen saturation for piglet with hypoxia-ischemia

Haishu Ding; Lan Huang; Chungchien Jen; Betau Hwang; Zhiguang Lee; Yichao Teng; Meizhi Zheng

doi:10.1117/12.575936

18 January 2005 Physiological meaning of cerebral oxygen saturation for piglet with hypoxia-ischemia

Haishu Ding, Lan Huang, Chungchien Jen, Betau Hwang, Zhiguang Lee, Yichao Teng, Meizhi Zheng

Proceedings Volume 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II; (2005) https://doi.org/10.1117/12.575936
Event: Photonics Asia, 2004, Beijing, China

Abstract

The physiological meaning of cerebral oxygen saturation absolute values and the oxygen metabolism of piglet with hypoxia-ischemia (HIE) were researched. The subjects were two piglets. During the total experiment of hypoxia then recovery, the regional cerebral tissue oxygen (rScO₂), pulse oxygen saturation (SpO₂) were detected non-invasively and the jugular oxygen saturation (SjO₂), arterial oxygen saturation (SaO₂) were given invasively. The results show that because SjO₂ was equal to or larger than rScO₂ and SaO₂ > ScO₂, rScO₂ cannot be determined by the weighted sum of SjO₂ and SaO₂ which had been presented in some papers. According to above-mentioned analysis, the ecchymoma and pathological changes of the vessels due to HIE may be another contribution of rScO₂. SjO₂ was correlated with SaO₂ (R=0.996 and 0.962 for two piglets) and the values of (SaO₂-SjO₂) are close to constants (29.3±8% and 30.3±8%).It means that because the subjects were under anesthesia, the oxygen consumption of cerebral tissue kept constants.

Citation Download Citation

Haishu Ding, Lan Huang, Chungchien Jen, Betau Hwang, Zhiguang Lee, Yichao Teng, and Meizhi Zheng "Physiological meaning of cerebral oxygen saturation for piglet with hypoxia-ischemia", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); https://doi.org/10.1117/12.575936

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