Interaction of few molecular motors transporting one cargo along filament

Mikhail M. Stolnitz; Alexey A. Kudryashoff

doi:10.1117/12.645771

3 March 2006 Interaction of few molecular motors transporting one cargo along filament

Mikhail M. Stolnitz, Alexey A. Kudryashoff

Proceedings Volume 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III; 60850V (2006) https://doi.org/10.1117/12.645771
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

Mathematical model of organelle transport by few molecular motors along filament is presented. Each motor is described as mechanochemical system, which consists of 3 elastically coupled Brownian particles and can be in different intrinsic states, jumping from one discrete filament bound site to other. Rigid or elastic coupling between motors and "cargo" are considered. Asymptotic analysis of organelle movement is performed and macroscopic parameters (average velocity and effective diffusion coefficient) are calculated.

Citation Download Citation

Mikhail M. Stolnitz and Alexey A. Kudryashoff "Interaction of few molecular motors transporting one cargo along filament", Proc. SPIE 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III, 60850V (3 March 2006); https://doi.org/10.1117/12.645771

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