Direct writing of a protein micro-array: lab-on-a-chip for multipurpose sensing

Massimiliano Rocchia; Stefano Borini; Andrea Mario Rossi; Mosè Rossi; Sabato D' Auria

doi:10.1117/12.697923

14 February 2007 Direct writing of a protein micro-array: lab-on-a-chip for multipurpose sensing

Massimiliano Rocchia, Stefano Borini, Andrea Mario Rossi, Mosè Rossi, Sabato D' Auria

Proceedings Volume 6444, Ultrasensitive and Single-Molecule Detection Technologies II; 644405 (2007) https://doi.org/10.1117/12.697923
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

A protein microarray has been realized on a porous silicon (PS) chip by means of electron beam irradiation using a standard SEM equipped with a nanopattern generator system. Two proteins have been used to generate the array: the glucose-binding protein (GBP) and the glutamine-binding protein (GlnBP), both isolated from Escherichia coli. The proteins functionality have been tested by means of a competitive assay.

Citation Download Citation

Massimiliano Rocchia, Stefano Borini, Andrea Mario Rossi, Mosè Rossi, and Sabato D' Auria "Direct writing of a protein micro-array: lab-on-a-chip for multipurpose sensing", Proc. SPIE 6444, Ultrasensitive and Single-Molecule Detection Technologies II, 644405 (14 February 2007); https://doi.org/10.1117/12.697923

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