Key technologies for LSPR-sensing microfluidic biochip

Hao Wang; Xiangang Luo; Hanmin Yao; Chunlei Du; Ze Yu Zhao; Shaoli Zhu

doi:10.1117/12.782969

21 November 2007 Key technologies for LSPR-sensing microfluidic biochip

Hao Wang, Xiangang Luo, Hanmin Yao, Chunlei Du, Ze Yu Zhao, Shaoli Zhu

Proceedings Volume 6724, 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Design, Manufacturing, and Testing of Micro- and Nano-Optical Devices and Systems; 67241V (2007) https://doi.org/10.1117/12.782969
Event: 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Large Mirrors and Telescopes, 2007, Chengdu, China

Abstract

New structures of micro-pump, biosensor in LOC (Lab-on-a-Chip) are studied. A round-path-chamber pumping principle is proposed to depress output fluctuation and increase output pressure of micro valve-less mechanical pump. Its prototype produces higher output pressure than the one with traditional column chamber. Two types of metal nanostructure array for LSPR (Localized Surface Plasmonic Resonance) biosensor were fabricated and tested, showing high sensitivity. Micro-channel is also discussed for realizing laminar flow above the metal nano-particles, to enable analytic samples to contact the metal nano-particles fully and stably.

Citation Download Citation

Hao Wang, Xiangang Luo, Hanmin Yao, Chunlei Du, Ze Yu Zhao, and Shaoli Zhu "Key technologies for LSPR-sensing microfluidic biochip", Proc. SPIE 6724, 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Design, Manufacturing, and Testing of Micro- and Nano-Optical Devices and Systems, 67241V (21 November 2007); https://doi.org/10.1117/12.782969

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