Electrical stimulation of peripheral nerves induces optical responses via skeletal muscle kinematics

M. Kelley Erb; Debbie K. Chen; Angelo Sassaroli; Sergio Fantini; Peter R. Bergethon

doi:10.1117/12.875145

2 March 2011 Electrical stimulation of peripheral nerves induces optical responses via skeletal muscle kinematics

M. Kelley Erb, Debbie K. Chen, Angelo Sassaroli, Sergio Fantini, Peter R. Bergethon

Proceedings Volume 7896, Optical Tomography and Spectroscopy of Tissue IX; 789609 (2011) https://doi.org/10.1117/12.875145
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We have previously reported an optical response in human subjects occurring at 100 ms following electrical stimulation of peripheral nerves. In the present study, an animal model has been created to directly investigate the myogenic components of the signal. In addition, experiments have been performed in human subjects to investigate the signal's neuroanatomical specificity, sensitivity to muscle motion, and spatial and spectral features. The results of this work suggest that the observed optical signal derives from stimulus-induced motion associated with muscle contraction and likely contains myological information of clinical value.

Citation Download Citation

M. Kelley Erb, Debbie K. Chen, Angelo Sassaroli, Sergio Fantini, and Peter R. Bergethon "Electrical stimulation of peripheral nerves induces optical responses via skeletal muscle kinematics", Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 789609 (2 March 2011); https://doi.org/10.1117/12.875145

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