Detection of longitudinal ulcer using roughness value for computer aided diagnosis of Crohn's disease

Masahiro Oda; Takayuki Kitasaka; Kazuhiro Furukawa; Osamu Watanabe; Takafumi Ando; Hidemi Goto; Kensaku Mori

doi:10.1117/12.877507

8 March 2011 Detection of longitudinal ulcer using roughness value for computer aided diagnosis of Crohn's disease

Masahiro Oda, Takayuki Kitasaka, Kazuhiro Furukawa, Osamu Watanabe, Takafumi Ando, Hidemi Goto, Kensaku Mori

Proceedings Volume 7963, Medical Imaging 2011: Computer-Aided Diagnosis; 79631E (2011) https://doi.org/10.1117/12.877507
Event: SPIE Medical Imaging, 2011, Lake Buena Vista (Orlando), Florida, United States

Abstract

The purpose of this paper is to present a new method to detect ulcers, which is one of the symptoms of Crohn's disease, from CT images. Crohn's disease is an inflammatory disease of the digestive tract. Crohn's disease commonly affects the small intestine. An optical or a capsule endoscope is used for small intestine examinations. However, these endoscopes cannot pass through intestinal stenosis parts in some cases. A CT image based diagnosis allows a physician to observe whole intestine even if intestinal stenosis exists. However, because of the complicated shape of the small and large intestines, understanding of shapes of the intestines and lesion positions are difficult in the CT image based diagnosis. Computer-aided diagnosis system for Crohn's disease having automated lesion detection is required for efficient diagnosis. We propose an automated method to detect ulcers from CT images. Longitudinal ulcers make rough surface of the small and large intestinal wall. The rough surface consists of combination of convex and concave parts on the intestinal wall. We detect convex and concave parts on the intestinal wall by a blob and an inverse-blob structure enhancement filters. A lot of convex and concave parts concentrate on roughed parts. We introduce a roughness value to differentiate convex and concave parts concentrated on the roughed parts from the other on the intestinal wall. The roughness value effectively reduces false positives of ulcer detection. Experimental results showed that the proposed method can detect convex and concave parts on the ulcers.

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Masahiro Oda, Takayuki Kitasaka, Kazuhiro Furukawa, Osamu Watanabe, Takafumi Ando, Hidemi Goto, and Kensaku Mori "Detection of longitudinal ulcer using roughness value for computer aided diagnosis of Crohn's disease", Proc. SPIE 7963, Medical Imaging 2011: Computer-Aided Diagnosis, 79631E (8 March 2011); https://doi.org/10.1117/12.877507

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KEYWORDS

Computer aided diagnosis and therapy

Intestine

Computed tomography

Endoscopes

Computing systems

Current controlled current source

Medical imaging

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