A computer-aided detection (CAD) system with a 3D algorithm for small acute intracranial hemorrhage

Ximing Wang; James Fernandez; Ruchi Deshpande; Joon K. Lee; Tao Chan; Brent Liu

doi:10.1117/12.910958

16 February 2012 A computer-aided detection (CAD) system with a 3D algorithm for small acute intracranial hemorrhage

Ximing Wang, James Fernandez, Ruchi Deshpande, Joon K. Lee, Tao Chan, Brent Liu

Proceedings Volume 8319, Medical Imaging 2012: Advanced PACS-based Imaging Informatics and Therapeutic Applications; 831913 (2012) https://doi.org/10.1117/12.910958
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

Acute Intracranial hemorrhage (AIH) requires urgent diagnosis in the emergency setting to mitigate eventual sequelae. However, experienced radiologists may not always be available to make a timely diagnosis. This is especially true for small AIH, defined as lesion smaller than 10 mm in size. A computer-aided detection (CAD) system for the detection of small AIH would facilitate timely diagnosis. A previously developed 2D algorithm shows high false positive rates in the evaluation based on LAC/USC cases, due to the limitation of setting up correct coordinate system for the knowledge-based classification system. To achieve a higher sensitivity and specificity, a new 3D algorithm is developed. The algorithm utilizes a top-hat transformation and dynamic threshold map to detect small AIH lesions. Several key structures of brain are detected and are used to set up a 3D anatomical coordinate system. A rule-based classification of the lesion detected is applied based on the anatomical coordinate system. For convenient evaluation in clinical environment, the CAD module is integrated with a stand-alone system. The CAD is evaluated by small AIH cases and matched normal collected in LAC/USC. The result of 3D CAD and the previous 2D CAD has been compared.

Citation Download Citation

Ximing Wang, James Fernandez, Ruchi Deshpande, Joon K. Lee, Tao Chan, and Brent Liu "A computer-aided detection (CAD) system with a 3D algorithm for small acute intracranial hemorrhage", Proc. SPIE 8319, Medical Imaging 2012: Advanced PACS-based Imaging Informatics and Therapeutic Applications, 831913 (16 February 2012); https://doi.org/10.1117/12.910958

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