Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

Guiying Ma; A. Ping Zhang; Guofeng Yan; Yinbing Bai; Yichuan Hu; Xuesong Ye

doi:10.1117/12.974989

7 November 2012 Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

Guiying Ma, A. Ping Zhang, Guofeng Yan, Yinbing Bai, Yichuan Hu, Xuesong Ye

Proceedings Volume 8421, OFS2012 22nd International Conference on Optical Fiber Sensors; 84215Q (2012) https://doi.org/10.1117/12.974989
Event: OFS2012 22nd International Conference on Optical Fiber Sensor, 2012, Beijing, China

Abstract

The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ~3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).

Citation Download Citation

Guiying Ma, A. Ping Zhang, Guofeng Yan, Yinbing Bai, Yichuan Hu, and Xuesong Ye "Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer", Proc. SPIE 8421, OFS2012 22nd International Conference on Optical Fiber Sensors, 84215Q (7 November 2012); https://doi.org/10.1117/12.974989

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available