Combined pixel classification and atlas-based segmentation of the ventricular system in brain CT Images

Pieter C. Vos; Ivana Išgum; J. Matthijs Biesbroek; Birgitta K. Velthuis; Max A. Viergever

doi:10.1117/12.2006222

13 March 2013 Combined pixel classification and atlas-based segmentation of the ventricular system in brain CT Images

Pieter C. Vos, Ivana Išgum, J. Matthijs Biesbroek, Birgitta K. Velthuis, Max A. Viergever

Proceedings Volume 8669, Medical Imaging 2013: Image Processing; 86691O (2013) https://doi.org/10.1117/12.2006222
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Accurate segmentation of the brain ventricular system in Computed Tomography (CT) images is useful in neurodiagnosis, providing quantitative measures on changes in ventricular size due to stroke. Manual segmentation, however, is a time-consuming, tedious task and is prone to large inter-observer variability. This study presents an automatic ventricle system segmentation method by combining the results of supervised pixel classification based on intensities with spatial information obtained from a multi-atlas-based segmentation method. The method is applied to follow-up brain CT images which were collected from a cohort of 20 patients with proven ischemic stroke. The automatic segmentation performance was evaluated in a leave-one-out strategy by comparing with manual segmentations. The results show that combining information obtained from pixel classification and multi-atlas-based segmentation significantly outperforms each method independently with a mean Dice coefficient index of 0.810.07.±

Citation Download Citation

Pieter C. Vos, Ivana Išgum, J. Matthijs Biesbroek, Birgitta K. Velthuis, and Max A. Viergever "Combined pixel classification and atlas-based segmentation of the ventricular system in brain CT Images", Proc. SPIE 8669, Medical Imaging 2013: Image Processing, 86691O (13 March 2013); https://doi.org/10.1117/12.2006222

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