The effect of picosecond laser pulses on redox-dependent processes in mice red blood cells studied in vivo

Olga Voronova; Tatyana Gening; Tatyana Abakumova; Aleksey Sysolyatin; Igor Zolotovskiy; Inna Antoneeva; Vladimir Ostatochnikov; Snezhanna Gening

doi:10.1117/12.2037877

26 February 2014 The effect of picosecond laser pulses on redox-dependent processes in mice red blood cells studied in vivo

Olga Voronova, Tatyana Gening, Tatyana Abakumova, Aleksey Sysolyatin, Igor Zolotovskiy, Inna Antoneeva, Vladimir Ostatochnikov, Snezhanna Gening

Author Affiliations +

Proceedings Volume 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications; 894114 (2014) https://doi.org/10.1117/12.2037877
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

The study highlights the effect of different modes of in vivo laser irradiation of mice using a PFL8LA laser with λ = 1560 nm, pulse duration of 1,4•10^-12 s, peak power of 3,72•10³ W and average output power of 20•10^-3 W on the lipid peroxidation parameters: conjugated dienes, ketodienes and conjugated trienes, malondialdehyde, Schiff bases and the activity of antioxidant enzymes - catalase, glutathione -S-transferase and superoxide dismutase in erythrocytes and plasma of mice. Two groups of mice received a total dose of 3.8 J/cm² per group, but the 1st group was irradiated only once, while the 2nd – four times. Significant differences in the parameters of the 1st and 2nd groups indicate different effects of the irradiation modes on redox-dependent processes in red blood cells of mice.

Citation Download Citation

Olga Voronova, Tatyana Gening, Tatyana Abakumova, Aleksey Sysolyatin, Igor Zolotovskiy, Inna Antoneeva, Vladimir Ostatochnikov, and Snezhanna Gening "The effect of picosecond laser pulses on redox-dependent processes in mice red blood cells studied in vivo", Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 894114 (26 February 2014); https://doi.org/10.1117/12.2037877

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