Influence of illumination position on image contrast in epi-optoacoustic imaging of human volunteers

Stefan Preisser; Gerrit Held; Sara Peeters; Michael Jaeger; Martin Frenz

doi:10.1117/12.2058126

3 March 2014 Influence of illumination position on image contrast in epi-optoacoustic imaging of human volunteers

Stefan Preisser, Gerrit Held, Sara Peeters, Michael Jaeger, Martin Frenz

Proceedings Volume 8943, Photons Plus Ultrasound: Imaging and Sensing 2014; 894346 (2014) https://doi.org/10.1117/12.2058126
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

In a multi-modal combination of optoacoustic (OA) and pulse-echo ultrasound (US) imaging, epi-mode irradiation with the irradiation optics integrated with the acoustic probe has the advantage of flexible clinical application on any part of the body that is already accessible to US. In epi-mode strong clutter limits the OA imaging depth to often around one centimetre. We investigated clutter in automated scanning of volunteer forearms using a real-time combined OA and US system. The results agree well with our theory that clutter arises from strong optical absorption at the location of tissue illumination. As a consequence, we show that an intermediate separation distance between imaging plane and irradiation region leads to superior OA image contrast compared to an irradiation close to the imaging plane.

Citation Download Citation

Stefan Preisser, Gerrit Held, Sara Peeters, Michael Jaeger, and Martin Frenz "Influence of illumination position on image contrast in epi-optoacoustic imaging of human volunteers", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 894346 (3 March 2014); https://doi.org/10.1117/12.2058126

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KEYWORDS

Ultrasonography

Tissue optics

Acoustics

Photoacoustic imaging

Absorption

Integrated optics

Applied physics

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