Flexible waveguide enabled single-channel terahertz endoscopic system

Pallavi Doradla; Karim Alavi; Cecil S. Joseph; Robert H. Giles

doi:10.1117/12.2079417

28 April 2015 Flexible waveguide enabled single-channel terahertz endoscopic system

Pallavi Doradla, Karim Alavi, Cecil S. Joseph, Robert H. Giles

Proceedings Volume 9362, Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications VIII; 93620D (2015) https://doi.org/10.1117/12.2079417
Event: SPIE OPTO, 2015, San Francisco, California, United States

Abstract

Colorectal cancer is the third most commonly diagnosed cancer in the world. The current standard of care for colorectal cancer is the conventional colonoscopy, which relies exclusively on the Physician’s experience. Continuous wave terahertz (THz) imaging has the potential to offer a safe, noninvasive medical imaging modality for detecting cancers. The current study demonstrates the design and development of a prototype terahertz endoscopic system based on flexible metal-coated terahertz waveguides. A CO₂ pumped Far-Infrared molecular gas laser operating at 584 GHz frequency was used for illuminating the tissue, while the reflected signals were detected using liquid Helium cooled silicon bolometer. The continuous-wave terahertz imaging system utilizes a single waveguide channel to transmit the radiation and collect the back reflected intrinsic terahertz signal from the sample and is capable of operation in both transmission and reflection modalities. The two dimensional reflectance images obtained using a prototype terahertz endoscopic system showed intrinsic contrast between cancerous and normal regions of the colorectal tissue, thereby demonstrating the potential impact of terahertz imaging for in vivo cancer detection.

Citation Download Citation

Pallavi Doradla, Karim Alavi, Cecil S. Joseph, and Robert H. Giles "Flexible waveguide enabled single-channel terahertz endoscopic system", Proc. SPIE 9362, Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications VIII, 93620D (28 April 2015); https://doi.org/10.1117/12.2079417

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