A method for tuning the excitation wavelength of an LED light source during fluorescence-based cystoscopy (Conference Presentation)

Lars R. Lindvold; Gregers G. Hermannn M.D.

doi:10.1117/12.2213412

27 April 2016 A method for tuning the excitation wavelength of an LED light source during fluorescence-based cystoscopy (Conference Presentation)

Lars R. Lindvold, Gregers G. Hermannn M.D.

Author Affiliations +

Proceedings Volume 9689, Photonic Therapeutics and Diagnostics XII; 96891P (2016) https://doi.org/10.1117/12.2213412
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

In clinical applications of fluorescence-guided endoscopy of the bladder (cystoscopy) it can be observed that the contrast in light from autofluorescence and from photodynamic diagnosis (PDD) varies from patient to patient. To compensate for this effect, a new method is presented for tuning the wavelength of a LED-based light source during fluorescence guided endoscopy of the bladder i.e. photodynamic diagnosis of bladder tumours. In the present embodiment, the wavelength of the LED source, developed in our laboratory, can be tuned to vary the excitation wavelength of both the sensitised fluorescence in the tumours (PDD) as well as the native fluorescence of the bladder mucosa and blood vessels. The contrast of the image observed through the CCD-camera attached to the cystoscope is thereby increased. In this way, patient to patient variations in autofluorescence and in sensitised fluorescence of tumours can be compensated for during fluorescence-guided cystoscopy in the clinic.

Conference Presentation

Citation Download Citation

Lars R. Lindvold and Gregers G. Hermannn M.D. "A method for tuning the excitation wavelength of an LED light source during fluorescence-based cystoscopy (Conference Presentation)", Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96891P (27 April 2016); https://doi.org/10.1117/12.2213412

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available