Lambertian nature of tissue phantoms for use as calibrators in near infrared fluorescence imaging

Maritoni Litorja; Simón Lorenzo; Banghe Zhu; Eva Sevick Muraca

doi:10.1117/12.2216324

10 March 2016 Lambertian nature of tissue phantoms for use as calibrators in near infrared fluorescence imaging

Maritoni Litorja, Simón Lorenzo, Banghe Zhu, Eva Sevick Muraca

Proceedings Volume 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II; 96960H (2016) https://doi.org/10.1117/12.2216324
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

The use of tissue phantoms as calibrators to transfer SI-referenced scale to an imager offers convenience, compared to other methods of calibration. The tissue phantoms are calibrated separately for radiance at emission wavelength per irradiance at excitation wavelength. This calibration is only performed at a single geometric configuration, typically with the detector normal to the sample. In the clinic however, the imager can be moved around, resulting in a geometric configuration different from the calibration configuration. In this study, radiometric measurements are made at different sample-imager angles to test whether the tissue phantoms are Lambertian and the angular limits to which the calibration values hold true.

Conference Presentation

Citation Download Citation

Maritoni Litorja, Simón Lorenzo, Banghe Zhu, and Eva Sevick Muraca "Lambertian nature of tissue phantoms for use as calibrators in near infrared fluorescence imaging", Proc. SPIE 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II, 96960H (10 March 2016); https://doi.org/10.1117/12.2216324

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