High-speed functional photoacoustic microscopy using a water-immersible two-axis torsion-bending scanner

Maomao Chen; Xiaoyu Duan; Bangxin Lan; Tri Vu; Xiaoyi Zhu; Qiangzhou Rong; Wei Yang; Ulrike Hoffmann; Jun Zou; Junjie Yao

doi:10.1117/12.2609803

7 March 2022 High-speed functional photoacoustic microscopy using a water-immersible two-axis torsion-bending scanner

Maomao Chen, Xiaoyu Duan, Bangxin Lan, Tri Vu, Xiaoyi Zhu, Qiangzhou Rong, Wei Yang, Ulrike Hoffmann, Jun Zou, Junjie Yao

Author Affiliations +

Proceedings Volume PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022; PC119602N (2022) https://doi.org/10.1117/12.2609803
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Optical-resolution photoacoustic microscopy (OR-PAM) can image biological tissues at micrometer level resolution. However, the imaging speed of traditional OR-PAM is often too slow for capturing dynamic information. In this work, we demonstrate a high-speed OR-PAM system using a water-immersible two-axis torsion-bending scanner, in which the fast axis employs the torsion scanning while the slow axis works at the bending mode. The system has achieved a cross-sectional frame rate of 400 Hz, and a volumetric imaging speed of 1 Hz over a field of view of 1.5 × 2.5 mm2. We have demonstrated high-speed OR-PAM of fast hemodynamic changes in vivo.

Conference Presentation

Citation Download Citation

Maomao Chen, Xiaoyu Duan, Bangxin Lan, Tri Vu, Xiaoyi Zhu, Qiangzhou Rong, Wei Yang, Ulrike Hoffmann, Jun Zou, and Junjie Yao "High-speed functional photoacoustic microscopy using a water-immersible two-axis torsion-bending scanner", Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC119602N (7 March 2022); https://doi.org/10.1117/12.2609803

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available