Ocular elastography by ambient pressure modulation

Sabine Kling

doi:10.1117/12.2611385

2 March 2022 Ocular elastography by ambient pressure modulation

Sabine Kling

Proceedings Volume PC11962, Optical Elastography and Tissue Biomechanics VIV; PC119620Q (2022) https://doi.org/10.1117/12.2611385
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Altered biomechanical properties are an important precursor for degenerative tissue pathologies. In the eye, diagnostic tools are demanded to be non-invasive, quickly-performed and of high resolution. To meet this need, a novel technique is presented based on an under-pressure chamber applying a homogenous mechanical load on the ocular shell similar to the intraocular pressure, and simultaneous phase-sensitive recording of axial displacements and strain by optical coherence tomography. Results are presented that visualize the instantaneous mechanical effect of patterned corneal cross-linking in ex vivo rat eyes, and the creep response of cornea and crystalline lens in an in vivo subject.

Conference Presentation

Citation Download Citation

Sabine Kling "Ocular elastography by ambient pressure modulation", Proc. SPIE PC11962, Optical Elastography and Tissue Biomechanics VIV, PC119620Q (2 March 2022); https://doi.org/10.1117/12.2611385

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