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17 March 2023 Model for skin response due to noxious heating using a spatial frequency domain imaging system with compact eye camera
Nandan Das, Saad Nagi, Keiichiro Kagawa, Rolf Saager
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Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520O (2023) https://doi.org/10.1117/12.2649804
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Detection of hemoglobin (tHb), water (tH2O), and microvascular perfusion dynamics is of great importance as these indicate early signs of tissue physiological changes related to diseases. We have developed a physiological model based on tissue absorption and scattering properties measured by a customized spatial frequency domain imaging (SFDI) system. We performed an in-vivo investigation to evaluate the imager’s ability to characterize dermal response under a noxious heating protocol. In this initial study, we found that noxious heating induced changes in extravascular water content, hemoglobin, and tissue morphology that can be interpreted as vascular perfusion and dilation, inflammation, and edema.
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Nandan Das, Saad Nagi, Keiichiro Kagawa, and Rolf Saager "Model for skin response due to noxious heating using a spatial frequency domain imaging system with compact eye camera", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520O (17 March 2023); https://doi.org/10.1117/12.2649804
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KEYWORDS
Imaging systems
Cameras
Tissues
Eye
Eye models
Scattering
Skin
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