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17 March 2023 Multifunctional biocompatible nanoplatforms for near infrared cancer theranostics (Conference Presentation)
Tymish Y. Ohulchanskyy
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Proceedings Volume PC12398, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV; PC1239809 (2023) https://doi.org/10.1117/12.2653118
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
The talk will present our recent results on development of multifunctional biocompatible nanoplatforms for cancer theranostics. The three nanoplatforms targeting tumors include polymeric nanoparticles (PNPs), nanoliposomes and protein nanocrystals; they can be equipped with NIR luminescence, photoacoustic (PA) and computed tomography (CT) imaging contrasts, along with PDT/PTT and chemotherapy modalities, which can be selectively activated by tumor microenvironment (TME). The talk will also demonstrate application of PNPs for visible or NIR fluorescence labeling of the systemically injected mesenchymal stem cells, which manifest tumor tropism in metastatic cancer animal model, allowing for fluorescence imaging based detection of primary tumor and metastases.
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Citation Download Citation
Tymish Y. Ohulchanskyy "Multifunctional biocompatible nanoplatforms for near infrared cancer theranostics (Conference Presentation)", Proc. SPIE PC12398, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV, PC1239809 (17 March 2023); https://doi.org/10.1117/12.2653118
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KEYWORDS
Near infrared
Cancer
Luminescence
Tumors
Photodynamic therapy
Computed tomography
Optical imaging
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