FLASH radiotherapy: a new cancer treatment modality and its challenges, physics, engineering, and biology

Magdalena Bazalova-Carter

doi:10.1117/12.2685149

4 October 2023 FLASH radiotherapy: a new cancer treatment modality and its challenges, physics, engineering, and biology

Magdalena Bazalova-Carter

Author Affiliations +

Proceedings Volume PC12694, Advances in X-Ray/EUV Optics and Components XVIII; PC1269401 (2023) https://doi.org/10.1117/12.2685149
Event: SPIE Optical Engineering + Applications, 2023, San Diego, California, United States

Abstract

FLASH radiotherapy delivered at ultrahigh dose-rates (UHDR) has shown promise in reducing normal tissue toxicity while maintaining tumor control, which could revolutionize cancer treatment. In this talk, some of the current research aimed towards clinical translation of FLASH and its challenges will be discussed. The history of FLASH radiotherapy from first in vitro experiments to the ongoing clinical trials will be presented. The engineering challenges of UHDR radiation sources and the need for accurate online dose measurements, where optical dosimetry might play an important role, will be discussed. Radiobiological hypotheses responsible for the FLASH effect will be briefly discussed.

Conference Presentation

Citation Download Citation

Magdalena Bazalova-Carter "FLASH radiotherapy: a new cancer treatment modality and its challenges, physics, engineering, and biology", Proc. SPIE PC12694, Advances in X-Ray/EUV Optics and Components XVIII, PC1269401 (4 October 2023); https://doi.org/10.1117/12.2685149

Access the abstract

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

Subscribe to Digital Library

Receive Erratum Email Alert

Keywords/Phrases

Search In:

Publication Years